Polyphenolic grape stalk and coffee extracts attenuate spinal cord injury-induced neuropathic pain development in ICR-CD1 female mice

Abstract More than half of spinal cord injury (SCI) patients develop central neuropathic pain (CNP), which is largely refractory to current treatments. Considering the preclinical evidence showing that polyphenolic compounds may exert antinociceptive effects, the present work aimed to study preventi...

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Bibliographic Details
Main Authors: Anna Bagó-Mas, Andrea Korimová, Meritxell Deulofeu, Enrique Verdú, Núria Fiol, Viktorie Svobodová, Petr Dubový, Pere Boadas-Vaello
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-19109-4