Red blood cell blood group A antigen level affects the ability of heparin and PfEMP1 antibodies to disrupt Plasmodium falciparum rosettes

Red blood cell blood group A antigen level affects the ability of heparin and PfEMP1 antibodies to disrupt Plasmodium falciparum rosettes

Abstract Background The histo-blood group ABO system has been associated with adverse outcomes in COVID-19, thromboembolic diseases and Plasmodium falciparum malaria. An integral part of the severe malaria pathogenesis is rosetting, the adherence of parasite infected red blood cells (RBCs) to uninfe...

Full description

Bibliographic Details
Main Authors: Pontus Hedberg, Madle Sirel, Kirsten Moll, Mpungu Steven Kiwuwa, Petter Höglund, Ulf Ribacke, Mats Wahlgren
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
Rosetting
Histo-blood group ABO system
Online Access:https://doi.org/10.1186/s12936-021-03975-w

Internet

https://doi.org/10.1186/s12936-021-03975-w

Similar Items