Synthetic promoter library for modulation of actinorhodin production in Streptomyces coelicolor A3(2).

The objective of this study was the application of the synthetic promoter library (SPL) technology for modulation of actinorhodin production in Streptomyces coelicolor A3(2). The SPL technology was used to optimize the expression of a pathway specific positive transcriptional regulator ActII orf4, w...

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Bibliographic Details
Main Authors: Sujata Vijay Sohoni, Alessandro Fazio, Christopher T Workman, Ivan Mijakovic, Anna Eliasson Lantz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4070896?pdf=render