Unveiling Tst3, a Multi-Target Gating Modifier Scorpion α Toxin from <i>Tityus stigmurus</i> Venom of Northeast Brazil: Evaluation and Comparison with Well-Studied Ts3 Toxin of <i>Tityus serrulatus</i>

Unveiling Tst3, a Multi-Target Gating Modifier Scorpion α Toxin from <i>Tityus stigmurus</i> Venom of Northeast Brazil: Evaluation and Comparison with Well-Studied Ts3 Toxin of <i>Tityus serrulatus</i>

Studies on the interaction sites of peptide toxins and ion channels typically involve site-directed mutations in toxins. However, natural mutant toxins exist among them, offering insights into how the evolutionary process has conserved crucial sequences for activities and molecular target selection....

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Bibliographic Details
Main Authors: Diogo Vieira Tibery, João Antonio Alves Nunes, Daniel Oliveira da Mata, Luis Felipe Santos Menezes, Adolfo Carlos Barros de Souza, Matheus de Freitas Fernandes-Pedrosa, Werner Treptow, Elisabeth Ferroni Schwartz
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Toxins
Subjects:
Tst3
Ts3
<i>Tityus</i>
α-toxin
scorpion
voltage gated sodium channels
Online Access:https://www.mdpi.com/2072-6651/16/6/257

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https://www.mdpi.com/2072-6651/16/6/257

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