A Comparative Analysis of Mouse Imprinted and Random X-Chromosome Inactivation

The mammalian sexes are distinguished by the X and Y chromosomes. Whereas males harbor one X and one Y chromosome, females harbor two X chromosomes. To equalize X-linked gene expression between the sexes, therian mammals have evolved X-chromosome inactivation as a dosage compensation mechanism. Duri...

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Bibliographic Details
Main Authors: Rebecca M. Malcore, Sundeep Kalantry
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Epigenomes
Subjects:
Online Access:https://www.mdpi.com/2075-4655/8/1/8