PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation

PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation

Summary: PIWI proteins are known as mediators of transposon silencing in animal germlines but are also found in adult pluripotent stem cells of highly regenerative animals, where they are essential for regeneration. Study of the nuclear PIWI protein SMEDWI-2 in the planarian somatic stem cell system...

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Bibliographic Details
Main Authors: Danyan Li, David H. Taylor, Josien C. van Wolfswinkel
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Cell Reports
Subjects:
stem cells
cell differentiation
piRNAs
PIWI
chromatin
planarian
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721012304

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http://www.sciencedirect.com/science/article/pii/S2211124721012304

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