Computational Insight of Phase Transformation and Drug Release Behaviour of Doxycycline-Loaded Ibuprofen-Based In-Situ Forming Gel

Computational Insight of Phase Transformation and Drug Release Behaviour of Doxycycline-Loaded Ibuprofen-Based In-Situ Forming Gel

This research investigates the gel formation behaviour and drug-controlling performance of doxycycline-loaded ibuprofen-based in-situ forming gels (DH-loaded IBU-based ISGs) for potential applications in periodontal treatment. The investigation begins by exploring the physical properties and gel for...

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Bibliographic Details
Main Authors: Napaphol Puyathorn, Poomipat Tamdee, Jitnapa Sirirak, Siriporn Okonogi, Thawatchai Phaechamud, Takron Chantadee
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceutics
Subjects:
doxycycline
ibuprofen
dimethyl sulfoxide
<i>N</i>-methyl-2-pyrrolidone
phase transformation
in-situ forming gels
Online Access:https://www.mdpi.com/1999-4923/15/9/2315

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https://www.mdpi.com/1999-4923/15/9/2315

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