Treg suppression of immunity within inflamed allogeneic grafts

CD4+Foxp3+ regulatory T cells (Tregs) restrain inflammation and immunity. However, the mechanisms underlying Treg suppressor function in inflamed nonlymphoid tissues remain largely unexplored. Here, we restricted immune responses to nonlymphoid tissues and used intravital microscopy to visualize Tre...

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Bibliographic Details
Main Authors: Hehua Dai, Andressa Pena, Lynne Bauer, Amanda Williams, Simon C. Watkins, Geoffrey Camirand
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-08-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.160579