Defining Transcriptomic Heterogeneity between Left and Right Ventricle-Derived Cardiac Fibroblasts

Defining Transcriptomic Heterogeneity between Left and Right Ventricle-Derived Cardiac Fibroblasts

Cardiac fibrosis is a key aspect of heart failure, leading to reduced ventricular compliance and impaired electrical conduction in the myocardium. Various pathophysiologic conditions can lead to fibrosis in the left ventricle (LV) and/or right ventricle (RV). Despite growing evidence to support the...

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Bibliographic Details
Main Authors: Michael Bradley Dewar, Fahad Ehsan, Aliya Izumi, Hangjun Zhang, Yu-Qing Zhou, Haisam Shah, Dylan Langburt, Hamsini Suresh, Tao Wang, Alison Hacker, Boris Hinz, Jesse Gillis, Mansoor Husain, Scott Patrick Heximer
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
cardiac fibroblast subpopulations
myofibroblast transdifferentiation
ventricular differences
RNA sequencing
pressure overload
Online Access:https://www.mdpi.com/2073-4409/13/4/327

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https://www.mdpi.com/2073-4409/13/4/327

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