The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT1 receptor to promote lung adenocarcinoma growth

The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT1 receptor to promote lung adenocarcinoma growth

Introduction: The human genome encodes two melatonin receptors (MT1 and MT2) that relay melatonin signals to cellular interior. Accumulating evidence has linked melatonin to multiple health benefits, among which its anticancer effects have become well-established. However, the implications of its re...

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Bibliographic Details
Main Authors: Qianhui Sun, Jinrui Zhang, Xiaoxi Li, Guoheng Yang, Shaoxuan Cheng, Dong Guo, Qingqing Zhang, Feng Sun, Feng Zhao, Dian Yang, Shanshan Wang, Taishu Wang, Shuyan Liu, Lijuan Zou, Yingqiu Zhang, Han Liu
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Advanced Research
Subjects:
Melatonin
MT1
USP8
Lung adenocarcinoma
Endocytosis
DUB
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222000285

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http://www.sciencedirect.com/science/article/pii/S2090123222000285

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