Positive feedback regulation of frizzled-7 expression robustly shapes a steep Wnt gradient in Xenopus heart development, together with sFRP1 and heparan sulfate
Secreted molecules called morphogens govern tissue patterning in a concentration-dependent manner. However, it is still unclear how reproducible patterning can be achieved with diffusing molecules, especially when that patterning concerns differentiation of thin tissues. Wnt is a morphogen that orga...
Main Authors: | , , , , , , |
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格式: | 文件 |
语言: | English |
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eLife Sciences Publications Ltd
2022-08-01
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丛编: | eLife |
主题: | |
在线阅读: | https://elifesciences.org/articles/73818 |