‘Mito-Bomb’: a novel mitochondria-targeting nanosystem for ferroptosis-boosted sonodynamic antitumor therapy

‘Mito-Bomb’: a novel mitochondria-targeting nanosystem for ferroptosis-boosted sonodynamic antitumor therapy

Mitochondria play an important role in regulating tumor cell death and metabolism so that they can be potential therapeutic targets. Sonodynamic therapy (SDT) represents an attractive antitumor method that induces apoptosis by producing highly toxic reactive oxygen species (ROS). Mitochondria-target...

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Bibliographic Details
Main Authors: Jianxin Wang, Zhiyu Zhao, Yan Liu, Xinyu Cao, Fuxin Li, Haitao Ran, Yang Cao, Changjun Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Drug Delivery
Subjects:
Sonodynamic therapy
ferroptosis
reactive oxygen species
GPX4
RSL-3
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2022.2126027

Internet

https://www.tandfonline.com/doi/10.1080/10717544.2022.2126027

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