Adoptive Cell Transfer of Allogeneic Epstein–Barr Virus-Specific T Lymphocytes for Treatment of Refractory EBV-Associated Posttransplant Smooth Muscle Tumors: A Case Report

Adoptive Cell Transfer of Allogeneic Epstein–Barr Virus-Specific T Lymphocytes for Treatment of Refractory EBV-Associated Posttransplant Smooth Muscle Tumors: A Case Report

Posttransplant smooth muscle tumors (PTSMTs) are rare Epstein–Barr virus (EBV)-associated neoplasms, mostly occurring after solid organ transplantation. Current therapeutic strategies include surgery and reduction of immunosuppressive medication. We describe for the first time a novel treatment appr...

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Bibliographic Details
Main Authors: Bjoern-Thore Hansen, Petra Bacher, Britta Eiz-Vesper, Steffen M. Heckl, Wolfram Klapper, Karoline Koch, Britta Maecker-Kolhoff, Claudia D. Baldus, Lars Fransecky
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
posttransplant smooth muscle tumors
PTSMT
smooth muscle tumor
adoptive cell transfer
virus-specific T cells
alloCELL
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.727814/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.727814/full

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