Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment

Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease that has a heavy social and economic impact on all societies and for which there is still no cure. Multitarget-directed ligands (MTDLs) seem to be a promising therapeutic strategy for finding an effective treatment for this disea...

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Bibliographic Details
Main Authors: Imen Dakhlaoui, Paul J. Bernard, Diana Pietrzak, Alexey Simakov, Maciej Maj, Bernard Refouvelet, Arnaud Béduneau, Raphaël Cornu, Krzysztof Jozwiak, Fakher Chabchoub, Isabel Iriepa, Helene Martin, José Marco-Contelles, Lhassane Ismaili
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
calcium channel antagonism
cholinesterase inhibition
Hantzsch reaction
multitarget directed ligands
Nrf2
Online Access:https://www.mdpi.com/1422-0067/24/11/9742

Internet

https://www.mdpi.com/1422-0067/24/11/9742

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