Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection.

Pseudomonas aeruginosa is an opportunistic pathogen involved in nosocomial infections. While a number of studies have demonstrated the roles of TLR2, TLR4 and TLR5 in host defense againt P. aeruginosa infection, the implication of TLR9 in this process has been overlooked. Here, we show that P. aerug...

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Bibliographic Details
Main Authors: Fatima Benmohamed, Mathieu Medina, Yong-Zheng Wu, Sophia Maschalidi, Gregory Jouvion, Laurent Guillemot, Michel Chignard, Bénédicte Manoury, Lhousseine Touqui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090466&type=printable