Phosphodiesterase 4D Depletion/Inhibition Exerts Anti-Oncogenic Properties in Hepatocellular Carcinoma

Phosphodiesterase 4D Depletion/Inhibition Exerts Anti-Oncogenic Properties in Hepatocellular Carcinoma

Isoform D of type 4 phosphodiesterase (PDE4D) has recently been associated with several human cancer types with the exception of human hepatocellular carcinoma (HCC). Here we explored the role of PDE4D in HCC. We found that PDE4D gene/protein were over-expressed in different samples of human HCCs co...

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Bibliographic Details
Main Authors: Federica Ragusa, Nadia Panera, Silvia Cardarelli, Marco Scarsella, Marzia Bianchi, Stefano Biagioni, Mauro Giorgi, Anna Alisi, Mara Massimi
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
PDE
HCC
cell proliferation
apoptosis
IGF2
Online Access:https://www.mdpi.com/2072-6694/13/9/2182

Internet

https://www.mdpi.com/2072-6694/13/9/2182

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