A study of Smad4, Smad6 and Smad7 in Surgically Resected Samples of Pancreatic Ductal Adenocarcinoma and Their Correlation with Clinicopathological Parameters and Patient Survival

A study of Smad4, Smad6 and Smad7 in Surgically Resected Samples of Pancreatic Ductal Adenocarcinoma and Their Correlation with Clinicopathological Parameters and Patient Survival

<p>Abstract</p> <p>Background</p> <p>Smad4 is the common mediator of the tumor suppressive functions of TGF-beta. Smad6 and Smad7 are the antagonists of the TGF-beta pathway. This study investigates the differential protein expressions of Smad4, Smad6 and Smad7 in tumor...

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Bibliographic Details
Main Authors: Singh Puneet, Srinivasan Radhika, Wig Jai, Radotra Bishan
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Research Notes
Subjects:
Pancreas
pancreatic adenocarcinoma
Smad4
Smad6
Smad7
clinicopathological parameters
prognosis
Online Access:http://www.biomedcentral.com/1756-0500/4/560

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http://www.biomedcentral.com/1756-0500/4/560

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