Interleukin 10 and TNFα synergistically enhance the expression of the G protein-coupled formylpeptide receptor 2 in microglia

Interleukin 10 and TNFα synergistically enhance the expression of the G protein-coupled formylpeptide receptor 2 in microglia

Microglia are important participants in inflammatory responses in the central nervous system. We previously observed that tumor necrosis factor alpha (TNFα) induces the expression of the formylpeptide receptor mFPR2 on microglial cells. This chemoattractant receptor mediates microglial cell chemotax...

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Bibliographic Details
Main Authors: Pablo Iribarren, Keqiang Chen, Wanghua Gong, Edward H. Cho, Stephen Lockett, Badarch Uranchimeg, Ji Ming Wang
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Neurobiology of Disease
Subjects:
Cytokines
Chemotaxis
Inflammation
Protein Kinases
Neuroimmunology
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107000897

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http://www.sciencedirect.com/science/article/pii/S0969996107000897

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