Single-cell RNA sequencing identifies a migratory keratinocyte subpopulation expressing THBS1 in epidermal wound healing

Summary: Keratinocyte differentiation is an intricate process that is regulated by multiple mediators. Using cultured human keratinocytes, we found that lysophosphatidic acid (LPA) induced the differentiation of a previously unsuspected keratinocyte subpopulation expressing the extracellular matrix...

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Bibliographic Details
Main Authors: Ratklao Siriwach, Anh Quynh Ngo, Makio Higuchi, Kentaro Arima, Satoko Sakamoto, Akira Watanabe, Shuh Narumiya, Dean Thumkeo
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422200400X