Functional Connectivity of Nucleus Accumbens and Medial Prefrontal Cortex With Other Brain Regions During Early-Abstinence Is Associated With Alcohol Dependence and Relapse: A Resting-Functional Magnetic Resonance Imaging Study

Functional Connectivity of Nucleus Accumbens and Medial Prefrontal Cortex With Other Brain Regions During Early-Abstinence Is Associated With Alcohol Dependence and Relapse: A Resting-Functional Magnetic Resonance Imaging Study

Background: Alcohol dependence (AD) is a chronic recurrent brain disease that causes a heavy disease burden worldwide, partly due to high relapse rates after detoxification. Verified biomarkers are not available for AD and its relapse, although the nucleus accumbens (NAc) and medial prefrontal corte...

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Main Authors: Xia Yang, Ya-jing Meng, Yu-jie Tao, Ren-hao Deng, Hui-yao Wang, Xiao-jing Li, Wei Wei, Yu Hua, Qiang Wang, Wei Deng, Lian-sheng Zhao, Xiao-hong Ma, Ming-li Li, Jia-jun Xu, Jing Li, Yan-song Liu, Zhen Tang, Xiang-dong Du, Jeremy W. Coid, Andrew J. Greenshaw, Tao Li, Wan-jun Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Psychiatry
Subjects:
alcohol dependence
relapse
relapse severity
predictor
rest-functional magnetic resonance imaging
functional connectivity
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.609458/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2021.609458/full

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