PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment
The poly (ADP-ribose) polymerase (PARP1) interacts with the telomere factor TRF1 and loss of PARP1 results in telomere fragility and impairment of helicases -TRF1 complex assembly.
Bibliographic Details
| Main Authors: |
C. Maresca,
A. Dello Stritto,
C. D’Angelo,
E. Petti,
A. Rizzo,
E. Vertecchi,
F. Berardinelli,
L. Bonanni,
A. Sgura,
A. Antoccia,
G. Graziani,
A. Biroccio,
E. Salvati |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2023-03-01
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| Series: | Communications Biology
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| Online Access: | https://doi.org/10.1038/s42003-023-04596-6
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