Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity

Transport of cargo into dendritic spines is required for synaptic plasticity. McVicker et al.describe a method of activity-dependent transport of a kinesin KIF1A and its cargo synaptotagmin-IV along microtubules that are transiently polymerized into dendritic spines.

Bibliographic Details
Main Authors: Derrick P. McVicker, Adam M. Awe, Karl E. Richters, Rebecca L. Wilson, Diana A. Cowdrey, Xindao Hu, Edwin R. Chapman, Erik W. Dent
Format: Article
Language:English
Published: Nature Portfolio 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12741