Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity
Transport of cargo into dendritic spines is required for synaptic plasticity. McVicker et al.describe a method of activity-dependent transport of a kinesin KIF1A and its cargo synaptotagmin-IV along microtubules that are transiently polymerized into dendritic spines.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2016-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms12741 |
| _version_ | 1818341820114927616 |
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| author | Derrick P. McVicker Adam M. Awe Karl E. Richters Rebecca L. Wilson Diana A. Cowdrey Xindao Hu Edwin R. Chapman Erik W. Dent |
| author_facet | Derrick P. McVicker Adam M. Awe Karl E. Richters Rebecca L. Wilson Diana A. Cowdrey Xindao Hu Edwin R. Chapman Erik W. Dent |
| author_sort | Derrick P. McVicker |
| collection | DOAJ |
| description | Transport of cargo into dendritic spines is required for synaptic plasticity. McVicker et al.describe a method of activity-dependent transport of a kinesin KIF1A and its cargo synaptotagmin-IV along microtubules that are transiently polymerized into dendritic spines. |
| first_indexed | 2024-12-13T16:04:52Z |
| format | Article |
| id | doaj.art-97d348539938458194a7b5686b6dbfb8 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-13T16:04:52Z |
| publishDate | 2016-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-97d348539938458194a7b5686b6dbfb82022-12-21T23:39:04ZengNature PortfolioNature Communications2041-17232016-09-017111310.1038/ncomms12741Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticityDerrick P. McVicker0Adam M. Awe1Karl E. Richters2Rebecca L. Wilson3Diana A. Cowdrey4Xindao Hu5Edwin R. Chapman6Erik W. Dent7Department of Neuroscience, University of Wisconsin, School of Medicine and Public HealthDepartment of Neuroscience, University of Wisconsin, School of Medicine and Public HealthDepartment of Neuroscience, University of Wisconsin, School of Medicine and Public HealthDepartment of Neuroscience, University of Wisconsin, School of Medicine and Public HealthDepartment of Neuroscience, University of Wisconsin, School of Medicine and Public HealthDepartment of Neuroscience, University of Wisconsin, School of Medicine and Public HealthDepartment of Neuroscience, University of Wisconsin, School of Medicine and Public HealthDepartment of Neuroscience, University of Wisconsin, School of Medicine and Public HealthTransport of cargo into dendritic spines is required for synaptic plasticity. McVicker et al.describe a method of activity-dependent transport of a kinesin KIF1A and its cargo synaptotagmin-IV along microtubules that are transiently polymerized into dendritic spines.https://doi.org/10.1038/ncomms12741 |
| spellingShingle | Derrick P. McVicker Adam M. Awe Karl E. Richters Rebecca L. Wilson Diana A. Cowdrey Xindao Hu Edwin R. Chapman Erik W. Dent Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity Nature Communications |
| title | Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity |
| title_full | Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity |
| title_fullStr | Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity |
| title_full_unstemmed | Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity |
| title_short | Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity |
| title_sort | transport of a kinesin cargo pair along microtubules into dendritic spines undergoing synaptic plasticity |
| url | https://doi.org/10.1038/ncomms12741 |
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