The Association of Polymorphisms in Genes Encoding Antioxidant Enzymes GPX1 (rs1050450), SOD2 (rs4880) and Transcriptional Factor Nrf2 (rs6721961) with the Risk and Development of Prostate Cancer

The Association of Polymorphisms in Genes Encoding Antioxidant Enzymes GPX1 (rs1050450), SOD2 (rs4880) and Transcriptional Factor Nrf2 (rs6721961) with the Risk and Development of Prostate Cancer

<i>Background and Objectives:</i> Mounting evidence implicates oxidative damage in prostate carcinogenesis, contributing to modifications of macromolecules that drive cellular malignant transformation. Functional single-nucleotide polymorphisms (SNPs) of enzymes involved in redox homeost...

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Bibliographic Details
Main Authors: Milica Djokic, Tanja Radic, Veljko Santric, Dejan Dragicevic, Sonja Suvakov, Smiljana Mihailovic, Vesna Stankovic, Milica Cekerevac, Tatjana Simic, Marina Nikitovic, Vesna Coric
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Medicina
Subjects:
reactive oxygen species
oxidative stress
antioxidant enzymes
prostate cancer
SNP
Online Access:https://www.mdpi.com/1648-9144/58/10/1414

Internet

https://www.mdpi.com/1648-9144/58/10/1414

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