Assessment of precision in growth inhibition assay (GIA) using human anti-PfRH5 antibodies

Assessment of precision in growth inhibition assay (GIA) using human anti-PfRH5 antibodies

Abstract Background For blood-stage malaria vaccine development, the in vitro growth inhibition assay (GIA) has been widely used to evaluate functionality of vaccine-induced antibodies (Ab), and Plasmodium falciparum reticulocyte-binding protein homolog 5 (RH5) is a leading blood-stage antigen. Howe...

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Bibliographic Details
Main Authors: Kazutoyo Miura, Ababacar Diouf, Michael P. Fay, Jordan R. Barrett, Ruth O. Payne, Ally I. Olotu, Angela M. Minassian, Sarah E. Silk, Simon J. Draper, Carole A. Long
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Malaria Journal
Subjects:
Growth inhibition assay
RH5
Plasmodium falciparum
Vaccine
Blood-stage
Precision
Online Access:https://doi.org/10.1186/s12936-023-04591-6

Internet

https://doi.org/10.1186/s12936-023-04591-6

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