Annexin A2 could enhance multidrug resistance by regulating NF-κB signaling pathway in pediatric neuroblastoma

Annexin A2 could enhance multidrug resistance by regulating NF-κB signaling pathway in pediatric neuroblastoma

Abstract Background Chemotherapy is one of major therapeutic regimens for neuroblastoma (NB) in children. However, recurrence and metastasis associated with poor prognosis caused by acquired multidrug resistance remains a challenge. There is a great need to achieve new insight into the molecular mec...

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Bibliographic Details
Main Authors: Yi Wang, Kai Chen, Yihong Cai, Yuanxia Cai, Xiaojun Yuan, Lifeng Wang, Zhixiang Wu, Yeming Wu
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Proteomics
ANXA2
Chemotherapy
Drug resistance
NF-κB
Neuroblastoma
Online Access:http://link.springer.com/article/10.1186/s13046-017-0581-6

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http://link.springer.com/article/10.1186/s13046-017-0581-6

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