Hsp90 Inhibitors Prevent HSV-1 Replication by Directly Targeting UL42-Hsp90 Complex

Herpes simplex virus type I (HSV-1) is a member of the Alphaherpesvirinae family, which could initiate labial herpes caused by the reactivation of HSV-1 primary infection, and secondary infection even causes herpes encephalitis. The study presented here demonstrates that Hsp90 inhibitors (AT-533 and...

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Váldodahkkit: Shurong Qin, Xiao Hu, Shimin Lin, Ji Xiao, Zhaoyang Wang, Jiaoyan Jia, Xiaowei Song, Kaisheng Liu, Zhe Ren, Yifei Wang
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Frontiers Media S.A. 2022-02-01
Ráidu:Frontiers in Microbiology
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fmicb.2021.797279/full