Integrating X-ray phase-contrast imaging and histology for comparative evaluation of breast tissue malignancies in virtual histology analysis

Abstract Detecting breast tissue alterations is essential for cancer diagnosis. However, inherent bidimensionality limits histological procedures’ effectiveness in identifying these changes. Our study applies a 3D virtual histology method based on X-ray phase-contrast microtomography (PhC $$\mu$$ μ...

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Bibliographic Details
Main Authors: Sandro Donato, Lucia Mariel Arana Peña, Fulvia Arfelli, Luca Brombal, Luisella Colmo, Renata Longo, Fulvia Martellani, Giuliana Tromba, Fabrizio Zanconati, Deborah Bonazza
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-56341-6