Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide

<p>Abstract</p> <p>Background</p> <p>Neurotoxic peptides derived from the protease-resistant core of the prion protein are used to model the pathogenesis of prion diseases. The current study characterised the ingestion, internalization and intracellular trafficking of a...

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Bibliographic Details
Main Authors: Williams Alun, Boshuizen Ronald, Bate Clive, Wilson Rona, Brewer James
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/8/99