de novo pyrimidine synthesis pathway inhibition reduces motility virulence of Pseudomonas aeruginosa despite complementation

Objectives: Finding alternative methods to overcome antibiotic resistance in the medically important bacterium Pseudomonas aeruginosa has become increasingly vital as antibiotic resistance becomes more difficult to overcome. DNA synthesis inhibition is a strategy that has been used to inhibit cancer...

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Bibliographic Details
Main Authors: Abdurahman A. Niazy, Rhodanne Nicole A. Lambarte, Hamdan S. Alghamdi
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Journal of King Saud University: Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S101836472200221X