IL-10-Secreting CD8<sup>+</sup> T Cells Specific for Human Cytomegalovirus (HCMV): Generation, Maintenance and Phenotype

IL-10-Secreting CD8<sup>+</sup> T Cells Specific for Human Cytomegalovirus (HCMV): Generation, Maintenance and Phenotype

HCMV-specific CD8<sup>+</sup> T-cells are potent anti-viral effector cells in HCMV infected individuals, but evidence from other viral infections suggests that CD8<sup>+</sup> T-cells can also produce the immunomodulatory cytokine IL-10. In this work we show that there are HC...

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Bibliographic Details
Main Authors: Sarah E. Jackson, George X. Sedikides, Veronika Romashova, Georgina Okecha, Ester B. M. Remmerswaal, Frederike J. Bemelman, John H. Sinclair, Mark R. Wills
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pathogens
Subjects:
human cytomegalovirus (HCMV)
CD8<sup>+</sup> T cells
IL-10 secretion
immunomodulation
T regulatory cells
Online Access:https://www.mdpi.com/2076-0817/11/12/1530

Internet

https://www.mdpi.com/2076-0817/11/12/1530

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