In Silico Discovery of GPCRs and GnRHRs as Novel Binding Receptors of SARS-CoV-2 Spike Protein Could Explain Neuroendocrine Disorders in COVID-19

In Silico Discovery of GPCRs and GnRHRs as Novel Binding Receptors of SARS-CoV-2 Spike Protein Could Explain Neuroendocrine Disorders in COVID-19

Despite the intense research work since the beginning of the pandemic, the pathogenesis of COVID-19 is not yet clearly understood. The previous mechanism of COVID-19, based on ACE2 tropism and explained through a single receptor, is insufficient to explain the pathogenesis due to the absence of angi...

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Bibliographic Details
Main Authors: Mahmoud Elkazzaz, Amr Ahmed, Yousry Esam-Eldin Abo-Amer, Tamer Hydara, Abdullah Haikal, Dina N. Abd El Razek, Wafa Ali Eltayb, Xiling Wang, Tomasz M. Karpiński, Dalia Hamza, Basit Jabbar, Israa M. Shamkh
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
COVID-19
GPCR
GnRHR
ACE2
spike protein
molecular docking
Online Access:https://www.mdpi.com/2076-393X/10/9/1500

Internet

https://www.mdpi.com/2076-393X/10/9/1500

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