PDIA4, a new endoplasmic reticulum stress protein, modulates insulin resistance and inflammation in skeletal muscle

PDIA4, a new endoplasmic reticulum stress protein, modulates insulin resistance and inflammation in skeletal muscle

IntroductionEndoplasmic reticulum (ER) stress has emerged as a key player in insulin resistance (IR) progression in skeletal muscle. Recent reports revealed that ER stress-induced the expression of protein disulfide isomerase family a member 4 (PDIA4), which may be involved in IR-related diseases. A...

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Bibliographic Details
Main Authors: Chien-Hsing Lee, Chi-Fu Chiang, Fu-Huang Lin, Feng-Chih Kuo, Sheng-Chiang Su, Chia-Luen Huang, Peng-Fei Li, Jhih-Syuan Liu, Chieh-Hua Lu, Chang-Hsun Hsieh, Yi-Jen Hung, Yi-Shing Shieh
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
Endoplasmic reticulum
insulin resistance
metformin
PDIA4
skeletal muscle
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1053882/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.1053882/full

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