ABHD17C, a metabolic and immune-related gene signature, predicts prognosis and anti-PD1 therapy response in pancreatic cancer

ABHD17C, a metabolic and immune-related gene signature, predicts prognosis and anti-PD1 therapy response in pancreatic cancer

Abstract Background PDAC is a highly malignant and immune-suppressive tumor, posing great challenges to therapy. Methods In this study, we utilized multi-center RNA sequencing and non-negative matrix factorization clustering (NMF) to identify a group of metabolism-related genes that could effectivel...

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Bibliographic Details
Main Authors: Weihao Zhang, Yongjie Xie, Xin Yu, Changfu Liu, Wei Gao, Wenge Xing, Tongguo Si
Format: Article
Language:English
Published: Springer 2023-06-01
Series:Discover Oncology
Subjects:
Gene signature
Metabolism
ABHD17C
Pancreatic cancer
Glycolysis
Immune microenvironment
Online Access:https://doi.org/10.1007/s12672-023-00690-7

Internet

https://doi.org/10.1007/s12672-023-00690-7

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