REST/NRSF Silencing Modifies Neuronal Gene Expression in siRNA-Treated HeLa Cells: A Preliminary Exploration in the Search for Neuronal Biomarkers of Cervical Cancer

REST/NRSF Silencing Modifies Neuronal Gene Expression in siRNA-Treated HeLa Cells: A Preliminary Exploration in the Search for Neuronal Biomarkers of Cervical Cancer

<i>Background and Objectives:</i> REST (RE1-silencing transcription factor) diminution is associated with transcriptional relaxation, neuropeptide overexpression, and phenotype redefinition in neuroendocrine cancers, but this effect has barely been studied in cervical cancer (CC). We pre...

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Bibliographic Details
Main Authors: Karen Cortés-Sarabia, Luz Del Carmen Alarcón-Romero, Miguel Ángel Mendoza-Catalán, Juan Carlos Carpio-Pedroza, Eduardo Castañeda-Saucedo, Carlos Ortuño-Pineda
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Medicina
Subjects:
neural phenotype
REST targets
transcriptional regulation
HeLa cells
cervical intraepithelial neoplasia
Online Access:https://www.mdpi.com/1648-9144/59/3/537

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https://www.mdpi.com/1648-9144/59/3/537

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