Detection of Vascular Notch3 Deposits in Unfixed Frozen Skin Biopsy Sample in CADASIL

Detection of Vascular Notch3 Deposits in Unfixed Frozen Skin Biopsy Sample in CADASIL

This study aimed to evaluate the utility of immunohistochemical staining of vascular Notch3 deposits in biopsied unfixed frozen skin samples from patients with suspected cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). We analyzed vascular Notch3...

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Bibliographic Details
Main Authors: Akihiko Ueda, Makoto Nakajima, Yohei Misumi, Keiichi Nakahara, Satoru Shinriki, Masayoshi Tasaki, Hirotaka Matsui, Mitsuharu Ueda
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neurology
Subjects:
CADASIL
Notch3 deposits
NOTCH3 variants
skin biopsy
immunohistochemistry
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.881528/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.881528/full

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