Gut microbiota contributes to bisphenol A-induced maternal intestinal and placental apoptosis, oxidative stress, and fetal growth restriction in pregnant ewe model by regulating gut-placental axis

Gut microbiota contributes to bisphenol A-induced maternal intestinal and placental apoptosis, oxidative stress, and fetal growth restriction in pregnant ewe model by regulating gut-placental axis

Abstract Background Bisphenol A (BPA) is an environmental contaminant with endocrine-disrupting properties that induce fetal growth restriction (FGR). Previous studies on pregnant ewes revealed that BPA exposure causes placental apoptosis and oxidative stress (OS) and decreases placental efficiency,...

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Bibliographic Details
Main Authors: Hao Zhang, Xia Zha, Bei Zhang, Yi Zheng, Mabrouk Elsabagh, Hongrong Wang, Mengzhi Wang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Microbiome
Subjects:
Bisphenol A
Fetal growth restriction
Gut microbiota
Gut-placental axis
Pregnant ewe
Online Access:https://doi.org/10.1186/s40168-024-01749-5

Internet

https://doi.org/10.1186/s40168-024-01749-5

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