Atorvastatin Can Modulate DNA Damage Repair in Endothelial Cells Exposed to Mitomycin C

Atorvastatin Can Modulate DNA Damage Repair in Endothelial Cells Exposed to Mitomycin C

HMG-CoA reductase inhibitors (statins) are widely used in the therapy of atherosclerosis and have a number of pleiotropic effects, including DNA repair regulation. We studied the cytogenetic damage and the expression of DNA repair genes (<i>DDB1</i>, <i>ERCC4</i>, and <i&g...

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Bibliographic Details
Main Authors: Maxim Sinitsky, Maxim Asanov, Anna Sinitskaya, Daria Shishkova, Maria Khutornaya, Varvara Minina, Anastasia Ponasenko
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
genotoxic stress
DNA damage
cytogenetics
micronucleus assay
gene expression
atorvastatin
Online Access:https://www.mdpi.com/1422-0067/24/7/6783

Internet

https://www.mdpi.com/1422-0067/24/7/6783

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