Pathogenesis and treatment of non-alcoholic steatohepatitis and its fibrosis
The initial presentation of non-alcoholic steatohepatitis (NASH) is hepatic steatosis. The dysfunction of lipid metabolism within hepatocytes caused by genetic factors, diet, and insulin resistance causes lipid accumulation. Lipotoxicity, oxidative stress, mitochondrial dysfunction, and endoplasmic...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Korean Association for the Study of the Liver
2023-01-01
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Series: | Clinical and Molecular Hepatology |
Subjects: | |
Online Access: | http://e-cmh.org/upload/pdf/cmh-2022-0237.pdf |