Pathogenesis and treatment of non-alcoholic steatohepatitis and its fibrosis

The initial presentation of non-alcoholic steatohepatitis (NASH) is hepatic steatosis. The dysfunction of lipid metabolism within hepatocytes caused by genetic factors, diet, and insulin resistance causes lipid accumulation. Lipotoxicity, oxidative stress, mitochondrial dysfunction, and endoplasmic...

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Bibliographic Details
Main Authors: Kuei-Chuan Lee, Pei-Shan Wu, Han-Chieh Lin
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2023-01-01
Series:Clinical and Molecular Hepatology
Subjects:
Online Access:http://e-cmh.org/upload/pdf/cmh-2022-0237.pdf