The crosstalk between autophagy and ferroptosis: what can we learn to target drug resistance in cancer?

Autophagy is a conserved intracellular degradation system that plays a dual role in cell death; thus, therapies targeting autophagy in cancer are somewhat controversial. Ferroptosis is a new form of regulated cell death featured with the iron-dependent accumulation of lethal lipid ROS. This pathway...

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Bibliographic Details
Main Authors: Yulu Zhou, Yong Shen, Cong Chen, Xinbing Sui, Jingjing Yang, Linbo Wang, Jichun Zhou
Format: Article
Language:English
Published: China Anti-Cancer Association 2019-12-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1504