Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer’s disease-related proteins

Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer’s disease-related proteins

Abstract Background Microglia are innate immune cells of the brain that perform phagocytic and inflammatory functions in disease conditions. Transcriptomic studies of acutely-isolated microglia have provided novel insights into their molecular and functional diversity in homeostatic and neurodegener...

Full description

Bibliographic Details
Main Authors: Srikant Rangaraju, Eric B. Dammer, Syed Ali Raza, Tianwen Gao, Hailian Xiao, Ranjita Betarbet, Duc M. Duong, James A. Webster, Chadwick M. Hales, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Molecular Neurodegeneration
Subjects:
Microglia
Neurodegeneration
Neuroinflammation
Immunology
Proteomics
Mass spectrometry
Online Access:http://link.springer.com/article/10.1186/s13024-018-0266-4

Internet

http://link.springer.com/article/10.1186/s13024-018-0266-4

Similar Items