Efficacy, dose–response, and aerosol delivery of dry powder synthetic lung surfactant treatment in surfactant-deficient rabbits and premature lambs

Efficacy, dose–response, and aerosol delivery of dry powder synthetic lung surfactant treatment in surfactant-deficient rabbits and premature lambs

Abstract Background Dry powder (DP) synthetic lung surfactant may be an effective means of noninvasive delivery of surfactant therapy to premature infants supported with nasal continuous positive airway pressure (nCPAP) in low-resource settings. Methods Four experimental DP surfactant formulations c...

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Bibliographic Details
Main Authors: Frans J. Walther, Alan J. Waring, Monicah Otieno, Robert M. DiBlasi
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Respiratory Research
Subjects:
Dry powder (DP) Synthetic lung surfactant
Surfactant protein B (SP-B)
Super Mini-B (SMB) peptide
B-YL peptide
Lactose
Trehalose
Online Access:https://doi.org/10.1186/s12931-022-02007-8

Internet

https://doi.org/10.1186/s12931-022-02007-8

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