Orbitofrontal cortex microRNAs support long-lasting heroin seeking behavior in male rats

Abstract Recovery from opioid use disorder (OUD) and maintenance of abstinence from opioid use is hampered by perseverant drug cravings that may persist for months after cessation of drug use. Drug cravings can intensify during the abstinence period, a phenomenon referred to as the ‘incubation of cr...

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Bibliographic Details
Main Authors: Mary Tresa Zanda, Gabriele Floris, Stephanie E. Sillivan
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02423-4