Live Imaging of Influenza Infection of the Trachea Reveals Dynamic Regulation of CD8+ T Cell Motility by Antigen.

During a primary influenza infection, cytotoxic CD8+ T cells need to infiltrate the infected airways and engage virus-infected epithelial cells. The factors that regulate T cell motility in the infected airway tissue are not well known. To more precisely study T cell infiltration of the airways, we...

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Bibliographic Details
Main Authors: Kris Lambert Emo, Young-Min Hyun, Emma Reilly, Christopher Barilla, Scott Gerber, Deborah Fowell, Minsoo Kim, David J Topham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5028057?pdf=render