Identification of a peptide antagonist of the FGF1–FGFR1 signaling axis by phage display selection

Overexpression of fibroblast growth factor receptor 1 (FGFR1) is a common aberration in lung and breast cancers and has necessitated the design of drugs targeting FGFR1‐dependent downstream signaling and FGFR1 ligand binding. To date, the major group of drugs being developed for treatment of FGFR1‐d...

Full description

Bibliographic Details
Main Authors: Magdalena Lipok, Anna Szlachcic, Kinga Kindela, Aleksandra Czyrek, Jacek Otlewski
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12618