Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis

Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis

Abstract Dietary fatty acids play a role in the pathogenesis of obesity-associated non-alcoholic fatty liver disease (NAFLD), which is associated with insulin resistance (IR). Fatty acid composition is critical for IR and subsequent NAFLD development. Extra-virgin olive oil (EVOO) is the main source...

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Bibliographic Details
Main Authors: Leticia Álvarez-Amor, Amparo Luque Sierra, Antonio Cárdenas, Lucía López-Bermudo, Javier López-Beas, Eloísa Andújar, Mónica Pérez-Alegre, Rocío Gallego-Durán, Lourdes M. Varela, Alejandro Martin-Montalvo, Genoveva Berná, Anabel Rojas, Mª José Robles-Frías, Abdelkrim Hmadcha, Manuel Romero-Gómez, Robert Kleemann, Franz Martín
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87761-3

Internet

https://doi.org/10.1038/s41598-021-87761-3

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