Genetic Polymorphisms of Glutathione S-Transferase P1 (GSTP1) and the Incidence of Anti-Tuberculosis Drug-Induced Hepatotoxicity.

Anti-tuberculosis drug-induced hepatotoxicity (ATDH) is one of the most common adverse effects associated with tuberculosis (TB) therapy. Animal studies have demonstrated important roles of glutathione S-transferases in the prevention of chemical-induced hepatotoxicity. The aim of this study was to...

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Bibliographic Details
Main Authors: Shouquan Wu, You-Juan Wang, Xiaoyan Tang, Yu Wang, Jingcan Wu, Guiyi Ji, Miaomiao Zhang, Guo Chen, Qianqian Liu, Andrew J Sandford, Jian-Qing He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4900521?pdf=render