Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis
Glaucoma is a serious complication of glucocorticoid (GC) therapy arising through elevations in intraocular pressure (IOP). Dexamethasone (DEX) is reported to contribute to elevated IOP through different effects on the trabecular meshwork but whether DEX contributes to glaucoma development through t...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2023-06-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.1177/09636897231177356 |