Effect of the Melanocortin 4-Receptor Ile269Asn Mutation on Weight Loss Response to Dietary, Phentermine and Bariatric Surgery Interventions

Effect of the Melanocortin 4-Receptor Ile269Asn Mutation on Weight Loss Response to Dietary, Phentermine and Bariatric Surgery Interventions

The loss of function melanocortin 4-receptor (<i>MC4R</i>) Ile269Asn mutation has been proposed as one of the most important genetic contributors to obesity in the Mexican population. However, whether patients bearing this mutation respond differently to weight loss treatments is unknown...

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Main Authors: Itzel G. Salazar-Valencia, Hugo Villamil-Ramírez, Francisco Barajas-Olmos, Martha Guevara-Cruz, Luis R. Macias-Kauffer, Humberto García-Ortiz, Omar Hernández-Vergara, David Alberto Díaz de Sandy-Galán, Paola León-Mimila, Federico Centeno-Cruz, Luis E. González-Salazar, Rocío Guizar-Heredia, Edgar Pichardo-Ontiveros, Leonor Jacobo-Albavera, Rosalinda Posadas-Sánchez, Gilberto Vargas-Alarcón, Rafael Velazquez-Cruz, Ruth Gutiérrez-Aguilar, Carlos Zerrweck, Héctor Isaac Rocha-González, Juan Gerardo Reyes-García, Miriam del C. Carrasco-Portugal, Francisco Javier Flores-Murrieta, Armando R. Tovar, Lorena Orozco, Teresa Villarreal-Molina, Samuel Canizales-Quinteros
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Genes
Subjects:
melanocortin-4-receptor
Ile269Asn-mutation
obesity
weight-loss
interventions
Online Access:https://www.mdpi.com/2073-4425/13/12/2267

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https://www.mdpi.com/2073-4425/13/12/2267

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