Molecular Insight into Drug Resistance Mechanism Conferred by Aberrant <i>PIK3CD</i> Splice Variant in African American Prostate Cancer
Targeting PI3Kδ has emerged as a promising therapy for hematologic and non-hematologic malignancies. Previously, we identified an oncogenic splice variant, <i>PIK3CD-S</i>, conferring Idelalisib resistance in African American (AA) prostate cancer (PCa). In the current study, we employed...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
|
| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/15/4/1337 |